Cell Biology at Scale 2024

When:
Where:
UCSF Byers Auditorium San Francisco, CA

Event Overview

This workshop is presented by the Chan Zuckerberg Biohub San Francisco in partnership with the Chan Zuckerberg Initiative.

Recent technological advances have transformed the scale at which cell biology can be conducted, from new imaging and “omics” strategies to the systematic engineering of genes and their expression. As a result, high-throughput, multiplexed approaches are greatly expanding the biological space that can be experimentally accessed. But the ability to conduct “cell biology at scale” is not simply an expansion of the number of experiments that can be performed – it represents a fundamental change in the way that such experiments can be conceived and the questions that can be answered.

To realize this potential, we need to re-evaluate core experimental goals, newly accessible biological questions, technological approaches, data collection, curation, dissemination, and effective strategies for computational analysis. We also need a collaborative, integrative, and interdisciplinary strategy to combine the capabilities and efforts from diverse laboratories for the robust sharing of techniques and datasets.

We are organizing the CB@S workshop to bring together a range of stakeholders from diverse disciplines to present recent developments and spark a robust discussion that will articulate key, actionable goals toward true cell biology at scale. For this workshop, we will also focus particularly on achieving large-scale cell biology across experimental scales – from the angstrom-level protein interactions that underlie cellular behaviors, to individual cells and differences across cell types, the interactions between cells within an organism, and emergent and collective cellular behaviors that are integrated at an organismal level.

Please register to attend in-person or virtually. A series of small talks will be selected from abstracts for in-person attendees.

Organizers

Paul Blainey

Broad Institute & MIT

Iain Cheeseman

Whitehead Institute & MIT

Jonah Cool

Chan Zuckerberg Initiative

Maneul Leonetti

CZ Biohub SF

Program

ALL TIMES IN PACIFIC TIME

Thursday, March 28

9 – 9:10 a.m.

Welcome Remarks

Steve Quake
Head of Science, Chan Zuckerberg Initiative

9:10 – 10:30 a.m.

Session 1: Intracellular Systems

Iain Cheeseman
Whitehead Institute & MIT

Emma Lundberg
Stanford University

Jan Ellenberg
EMBL

Lucas Pelkmans
University of Zürich

10:30 – 11 a.m.

Coffee Break

11 a.m. – 12:05 p.m.

Session 2: Cellular Dynamics – from Molecules to Organisms

Nike Walther
UC Berkeley

Samantha Morris
Washington University St. Louis

Sarah Bowling
Stanford University

Loïc Royer
CZ Biohub SF

12:10 – 1 p.m.

Lunch

1 – 2:15 p.m.

Session 3: Models & Networks

Trey Ideker
UC San Diego

Christina Theodoris
Gladstone Institutes

Markus Covert
Stanford University

Hana El-Samad
Altos Labs & UCSF

2:15 – 2:30 p.m.

Coffee Break

2:30 – 4 p.m.

Session 4: Proteins: Interactions, Remodeling & Predictions

Mikko Taipale
University of Toronto

Jared Rutter
The University of Utah & HHMI

Danielle Swaney
UCSF

Duo Peng
CZ Biohub SF

Erika Alden DeBenedictis
The Francis Crick Institute

4 – 4:20 p.m.

Coffee Break

4:20 – 5:15 p.m.

Session 5: Engineering & Physics for Cell Biology at Scale

Paul Blainey
Broad Institute & MIT

Taka Kudo
Genentech

Julie Theriot
University of Washington & HHMI

5:15 – 6:30 p.m.

Reception

Whitehead Institute

Presented in Partnership With

Contact

Email cbas2024@czbiohub.org