Biohub

Cell Biology at Scale 2025

Discussions to articulate actionable goals toward true cell biology at scale.

When:
–
Where:
West End Labs 125 W End Ave, New York, NY 10023

Event Overview

The Cell Biology at Scale (CB@S) meeting is co-hosted by the Chan Zuckerberg Biohub New York and Chan Zuckerberg Initiative and aims to bring together a range of stakeholders from diverse disciplines to present recent developments and spark a robust discussion that will articulate key, actionable goals toward true cell biology at scale. Conducting cell biology at scale is not simply an expansion of the number of experiments that can be performed – it represents a fundamental change in the way that such experiments can be conceived and the questions that can be answered. To realize this potential, the field needs to re-evaluate core experimental goals, ask newly accessible biological questions, and adopt scalable technologies for data collection, curation, dissemination, and computational analysis. There is also a need for a collaborative, integrative, and interdisciplinary strategy to combine the capabilities and efforts from diverse laboratories for the robust sharing of techniques or integration of datasets.

Three years ago, we started the CB@S meetings as a first step toward achieving this vision. Every year brings a different geographic location and new scientific topics. This year we hope to touch on a number of themes including:

  • Biological dynamics across scales
  • In vivo perturbation technologies
  • Synthetic biology, organelles and DNA assembly
  • Sequence-to-function models
  • Multi-modal measurements and modeling

Abstract Submission

Attendees are encouraged to submit an abstract for a short talk which would take place on July 31. Abstracts should be no more than 250 words and must be submitted via the registration form by June 13, 2025 for consideration. Applicants will be notified if their abstract is accepted by July 1, 2025.

Program

ALL TIMES IN EASTERN TIME

8 – 9 a.m.

Breakfast

Doors open at 8 a.m.

9 – 9:15 a.m.

Welcome Remarks

Andrea Califano – Chan Zuckerberg Biohub New York
Jonah Cool – Chan Zuckerberg Initiative

9:15 – 10:45 a.m.

Session 1: CB@S Turns 3

Paul Blainey – MIT/Broad
Samara Reck-Peterson – UC San Diego and HHMI
Rahul Satija – NYU
Britt Adamson – Princeton University
Noorsher Ahmed – Stanford University

10:45 – 11:15 a.m.

Coffee Break

11:15 a.m. – 12:30 p.m.

Session 2: Perturbations at Scale

Jonathan Weissman – MIT/Whitehead Institute and HHMI
Brian Brown – Mount Sinai
Peter Sims – Columbia University
Jessica Mella – UCSF

12:30 – 1:30 p.m.

Lunch

1:30 – 3 p.m.

Session 3: Modeling at Scale

Anne Carpenter – The Broad Institute
Eric Xing – Carnegie Mellon
Dana Pe’er – Memorial Sloan Kettering and HHMI
Jian Ma – Carnegie Mellon
Jialong Jiang – The Rockefeller University

3 – 3:30 p.m.

Coffee Break

3:30 – 5 p.m.

Session 4: Synthetic Biology at Scale

Emma Farley – UC San Diego
Clifford P.Brangwynne – Princeton University and HHMI
Jef Boeke – NYU
Gabriel Victora – The Rockefeller University and HHMI
Samir Amin – Yale University

5 – 5:15 p.m.

Closing Remarks

Iain Cheeseman – MIT/Whitehead Institute
Manuel Leonetti – Chan Zuckerberg Biohub San Francisco

5:15 – 6:30 p.m.

Reception

Organizers

Paul Blainey

MIT/Broad

Andrea Califano

CZ Biohub New York
Iain Cheeseman

Iain Cheeseman

MIT/Whitehead

Jonah Cool

Chan Zuckerberg Initiative
Headshot of Manuel Leonetti

Manuel Leonetti

CZ Biohub San Francisco
Peter Sims

Peter Sims

Columbia University

Location

Contact

Questions or comments can be emailed to the event organizers at events@ny.czbiohub.org.