Physics of Life Symposium 2024

Integrating physics and biology to understand the complex phenomena of life.

When:
Where:
San Francisco (and limited virtual livestream)

Event Overview

Living systems span multiple scales and levels of organization and display phenomena that often have no analog in the inanimate world. But for the last 500 years, physics has been focused on non-living matter. The physics of living systems is emerging as a new field, promising not only to reveal new insights about the inner workings of living systems, but also to push the limits of physics itself in the context of, for example, non-equilibrium physics and active matter research.

The Physics of Life Symposium aims to bring together researchers interested in leveraging the tools, approaches, and style of inquiry of physics to the complex and beautiful phenomena of life. Our objective is to nucleate a diverse and vibrant community of physical biologists in the San Francisco Bay Area, with the CZ Biohub SF as the convergence point for the exchange of ideas in an atmosphere that fosters collaborative research.

View videos from the first Physics of Life Symposium held in January 2023 here.

Keynote Speaker

Lead Organizers

Adrian Jacobo

Adrian Jacobo, Ph.D.

Group Leader, Quantitative Tissue Morphogenesis at CZ Biohub SF
Hernan Garcia

Hernan Garcia, Ph.D.

Associate Professor of Biophysics, Genetics, Genomics and Developmental Biology at UC Berkeley

Scientific Organizing Committee

CZ Biohub SF

Akilandeswari Balasubramanian

Stanford University

Griffin Chure

UC Berkeley

Hernan Garcia, Ph.D.

UC Berkeley

Andrea Herman

CZ Biohub SF

Adrian Jacobo, Ph.D.

UC Santa Cruz

Manasa Kesapragada

Stanford University

Charlie Lang

UC Berkeley

Brandon Schlomann

CZ Biohub SF

Deepika Sundarraman

Program

Wednesday, September 25

8 a.m.

Registration Opens

8 – 9:15 a.m.

Light breakfast (provided)

9:20 – 9:30 a.m.

Welcome Remarks

9:30 – 10:15 a.m.

Keynote Address

M. Lisa Manning, Ph.D., Syracuse University
William R. Kenan, Jr., Professor of Physics at Syracuse University in Syracuse, New York. Prof. Manning’s research uses simulations and theory to model the emergent properties of biological tissues

10:15 – 10:45 a.m.

Coffee Break

10:45 a.m. – 12:15 p.m.

Submitted 15-Minute Talks

Jude Lee, Stanford University
“Ultra-resolution, multi-scale live imaging of the 3D genome, folded by motor proteins”

Megan Kober, UC Berkeley
“Fructose-2,6-Bisphosphate: Maker or Breaker of Glycolytic Regulation?”

Henry De Belly, UCSF
“Actin and membrane act as an integrated system to globally coordinate cell polarity during cell migration”

Ksenia Zlobina, UC Santa Cruz
“Understanding Life System Dynamics through Multiomics”

Gabriel Sturm, UC Berkeley
“Mitochondrial Pearling: an emerging class of organelle dynamics explained by a biophysical pearling instability”

12:15 – 1:45 p.m.

Lunch

1:45 – 3:30 p.m.

Submitted 15-Minute Talks

Zuben Scott, UCSD
“The endoplasmic reticulum as an active liquid network”

Jo-Hsi Huang, Stanford University
“Robust trigger wave speed in Xenopus cytoplasmic extracts”

Kate Cavanaugh, UCSF
“A core mechanical defect underlies the age-related dampening of implantation potential”

Vasudha Srivastava, UCSF
“Engineering the tissue structural ensemble: Mechanical fluctuations regulate the extent of structural order in tissues”

Austin Lefebvre, Calico Life Sciences
“From Voxels to Networks: A Comprehensive Tool for Physical Modeling of Cellular Organization”

Zhengda Li, Stanford University
“Geometrical constraints on apoptosis propagation”

Laura Persson, UCSF
“Physics Lessons From Worms: The role of electromagnetic fields in evaporation-sensing for long-range detection of water”

3:30 – 4 p.m.

Coffee Breaks

4 – 5 p.m.

Submitted 3-Minute Lightning Talks

Camilla Teng, UCSF
“Unveiling actomyosin cytoskeletal and adhesion dynamics in mammalian tissue fusion”

Bertie Ansell, Stanford University
“Structural Architecture of Ectomycorrhizal-Bacterial Interactions Viewed by High Resolution Electron Tomography”

Amir Bitran, UC Berkeley
“Towards a detailed molecular picture of non-equilibrium protein folding during real-time translation”

Neha Khetan, UCSF
“Quantitative analysis of IdU induced amplification in transcriptional noise using scRNA-seq and smRNA-FISH”

Aidan Cabral, Stanford University
“Chromatin architecture modulates cell mechanics”

Thomas Graham, UC Berkeley
“Single-molecule live imaging of endogenous protein interactions using proximity-assisted photoactivation (PAPA)”

Patrick Zager, UCSF
“Excess Membrane Buffers the Rate of Cell Shape Change in Neutrophils”

Tomoko Oshima, Stanford University
“Developing a Xenopus Egg Extract System to Reconstitute Prion Dynamics”

Xing Liang, Stanford University
“How dendrites establish and maintain their microtubule array?”

Manasa Kesapragada, UCSF
“Data-driven classification of cell subtypes based on time-lapse microscopy of single cells”

Manuel Razo-Mejia, Stanford University
“Evolving Solutions: In-Silico Evolution Meets Deep Learning for Rapid Adaptation”

Dong Shin (Chris) You, Stanford University
“Cell size increase leads to transcriptome remodeling”

Saehyun Choi, UC Berkeley
“Signaling protein clustering and condensation in the T cell signaling pathway”

Caleb Rux, UCSF
“Force-dependent spindle microtubule damage, remodeling and stabilization”

4:50 – 5 p.m.

Closing Remarks

5 – 6 p.m.

Poster Session & Social Hour

Food and beverage provided

Submitted Talks and Posters

Students, postdocs, and early career researchers (non-PIs) are encouraged to share their work via a 15-minute talk or 3-minute lightning talk, and all attendees are encouraged to present a poster. More details and the submission process are included during registration. The talk abstract submission window closed Thursday, August 15. Posters abstracts will be accepted through September 16.

Location

Contact

Questions? Contact the event organizers at physicsoflife@czbiohub.org