Research

We believe in sharing the research findings of our teams and partners openly to accelerate understanding of human health and disease. We strongly encourage researchers to deposit manuscripts as preprints before peer review to increase access to research findings and to communicate results more quickly. Since 2015, we have supported more than 8,000 publications.

91 Results
  • Multidimensional Analysis of the Adult Human Heart in Health and Disease Using Hierarchical Phase-Contrast Tomography

    Joseph Brunet, Andrew Cook, Claire Walsh et al. (2024) | Radiology

  • Insights and Impact From Five Cycles of Essential Open Source Software for Science

    Kate Hertweck, Carly Strasser, Dario Taraborelli (2024)

  • Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein

    Nils Birkholz, Kotaro Kamata, Maximilian Feussner et al. (2024) | Nature

  • Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus

    Law, C., Wacleche, V.S., Cao, Y. et al. (2024) | Nature

  • The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

    Femke M. Feringa, Sascha J. Koppes-den Hertog, Lian Wang et al. (2024) | bioRxiv

  • More Than a Phase: Uncovering the Structure of Materials with Electron Phase Retrieval Techniques

    Stephanie Ribet, Georgios Varnavides, Yue Yu et al. (2024) | Microscopy and Microanalysis

  • Towards More Efficient Use of Electrons: Demonstrating Cryo-4D-STEM Phase Imaging Techniques on Thick and Thin Biological Specimens, from Organelles to Proteins

    Yue Yu, Stephanie M Ribet, Georgios Varnavides et al. (2024) | Microscopy and Microanalysis

  • Single-cell analysis of human diversity in circulating immune cells

    Kian Hong Kock, Le Min Tan, Kyung Yeon Han et al. (2024) | bioRxiv

  • T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis

    Kedia, S., Ji, H., Feng, R. et al. (2024) | Nature Neuroscience

  • protoSpaceJAM: an open-source, customizable and web-accessible design platform for CRISPR/Cas insertional knock-in

    Duo Peng, Madhuri Vangipuram, Joan Wong, Manuel D Leonetti (2024) | Nucleic Acids Research

  • Mantis: high-throughput 4D imaging and analysis of the molecular and physical architecture of cells

    Ivan E. Ivanov, Eduardo Hirata-Miyasaki, Talon Chandler et al. (2024) | bioRxiv

  • Data-driven regularization lowers the size barrier of cryo-EM structure determination

    Kimanius, D., Jamali, K., Wilkinson, M.E. et al. (2024) | Nature Methods