Research
We believe in sharing the research findings of our teams and partners openly to accelerate understanding of human health and disease. We strongly encourage researchers to deposit manuscripts as preprints before peer review to increase access to research findings and to communicate results more quickly. Since 2015, we have supported more than 8,000 publications.
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Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle-mediated mRNA delivery in preclinical models
Kangfu Chen, Wenhan Wang, Amber Lennon, et al. (2026) | Science Translational Medicine
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Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection
Roham Parsa, Arpita Sushil (2026) | Nature Immunology
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AI-Guided CRISPR Screen Accelerates Discovery of New Drug Targets
Mushaine Shih, Amber Lennon, Jason Perera, et al. (2026) | bioRxiv
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Virtual Cells Need Context, Not Just Scale
Payam Dibaeinia, Sudarshan Babu, Mei Knudson, et al. (2026) | bioRxiv
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DecoderTCR: Compositional Pretraining and Entropy-Guided Decoding for TCR-pMHC Interactions
Ben Lai, Melissa Englund, Ramit Bharanikumar, et al. (2026) | bioRxiv
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Scalable Single-Cell Gene Expression Generation with Latent Diffusion Models
Giovanni Palla, Sudarshan Babu, Payam Dibaeinia, et al. (2025) | arXiv
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VariantFormer: A hierarchical transformer integrating DNA sequences with genetic variations and regulatory landscapes for personalized gene expression prediction
Sayan Ghosal, Youssef Barhomi, Tejaswini Ganapathi, et al. (2025) | bioRxiv
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A path towards AI-scale, interoperable biological data
Brian Aevermann, Andrea Califano, Chi-Li Chiu, et al. (2025) | arXiv
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Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection
Roham Parsa, Helder Assis, Tiago B.R. de Castro, et al. (2025) | bioRxiv
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rbio1-training scientific reasoning LLMs with biological world models as soft verifiers
Ana-Maria Istrate, Fausto Milletari, Fabrizio Castrotorres, et al. (2025) | bioRxiv
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GREmLN: A Cellular Regulatory Network-Aware Transcriptomics Foundation Model
Mingxuan Zhang, Vinay Swamy, Rowan Cassius, et al. (2025) | bioRxiv
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Variational Control for Guidance in Diffusion Models
Kushagra Pandey, Farrin Marouf Sofian, Felix Draxler, et al. (2025) | ICML 2025