Research

We believe in sharing the research findings of our teams and partners openly to accelerate understanding of human health and disease. We strongly encourage researchers to deposit manuscripts as preprints before peer review to increase access to research findings and to communicate results more quickly. Since 2015, we have supported more than 8,000 publications.

20 Results
  • Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle-mediated mRNA delivery in preclinical models

    Kangfu Chen, Wenhan Wang, Amber Lennon, et al. (2026) | Science Translational Medicine

  • AI-Guided CRISPR Screen Accelerates Discovery of New Drug Targets

    Mushaine Shih, Amber Lennon, Jason Perera, et al. (2026) | bioRxiv

  • Virtual Cells Need Context, Not Just Scale

    Payam Dibaeinia, Sudarshan Babu, Mei Knudson, et al. (2026) | bioRxiv

  • DecoderTCR: Compositional Pretraining and Entropy-Guided Decoding for TCR-pMHC Interactions

    Ben Lai, Melissa Englund, Ramit Bharanikumar, et al. (2026) | bioRxiv

  • GREmLN: A Cellular Regulatory Network-Aware Transcriptomics Foundation Model

    Mingxuan Zhang, Vinay Swamy, Rowan Cassius, et al. (2025) | bioRxiv

  • The regulatory architecture of the primed pluripotent cell state

    Li, B.I., Alvarez, M.J., Zhao, H. et al.(2025) | Nature Communications

  • Systems Human Immunology and AI: Immune Setpoint and Immune Health

    Yona Lei, John Tsang (2025) | Annual Review of Immunology

  • KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection

    Fagerberg E, Attanasio J, Dien C, et al. (2025) | Science

  • Exon inclusion signatures enable accurate estimation of splicing factor activity.

    Anglada-Girotto M, Moakley DF, Zhang C, Miravet-Verde S, et al. (2025) | bioRxiv

  • Active-reset protein sensors enable continuous in vivo monitoring of inflammation

    H. Zargartalebi, S. Mirzaie, A. Ghavaminejad et al. (2024) | Science

  • Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma

    Gallitto M, Zhang X, De Los Santos G, et al.(2024) | Society for Neuro-Oncology

  • Genome-wide studies define new genetic mechanisms of IgA vasculitis.

    Liu L, Zhu L, Monteiro-Martins S, et al. (2024) | medRxiv