Advanced Single Cell Technology Platform
Building single-cell tools to decode immune complexity.
We are a team of scientists, engineers, and computational biologists building next-generation tools for single-cell analysis. Our goal is to measure more features from more cells, making it possible to study biology at greater scale and resolution.
We apply our tools to aid in the understanding of the immune system. Immune cells integrate signals from across the body, respond dynamically to disease, and carry rich information about biological state. We are building tools to read out that information and, over time, to use the immune system as a sensor of health and disease. We are based at the Biohub in New York and work closely with collaborators across partner institutions and scientific disciplines.
Multiomics at Scale
Cells encode information across many molecular and functional layers. We develop new approaches to measure these layers at single-cell resolution and build high-throughput, integrated workflows that can scale to large experiments.
Together, these data provide insight into cellular function and create a foundation for predictive models of cell behavior, including AI-based virtual cell models.
Current areas of particular interest include:
- High-throughput fixed-cell scATAC-seq
- Measurement of intracellular proteins
- Microdroplet encapsulation to enable expanded multiomic capabilities
- Coupled longitudinal live-cell imaging with single-cell transcriptomic profiling
- Live-cell morphological analysis
- Scalable single-cell perturbation profiling
Research Sites
We are primarily located in the Studebaker building located at 615 W 131th St. in New York City. Our group also operates research sites at our partner locations at Yale and Columbia, providing resources that support Biohub-aligned research on those campuses.
Our Team
