Research
We believe in sharing the research findings of our teams and partners openly to accelerate understanding of human health and disease. We strongly encourage researchers to deposit manuscripts as preprints before peer review to increase access to research findings and to communicate results more quickly. Since 2015, we have supported more than 8,000 publications.
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Isotype-aware inference of B cell clonal lineage trees from single-cell sequencing data
Leah L. Weber, Derek Reiman, Mrinmoy S. Roddur et al. (2024) | Cell Genomics
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Dose-Efficient Cryo-Electron Microscopy for Thick Samples Using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single Particles
Yue Yu, Katherine A. Spoth, Michael Colletta et al. (2024) | bioRxiv
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DynaMight: estimating molecular motions with improved reconstruction from cryo-EM images
Johannes Schwab, Dari Kimanius, Alister Burt et al. (2024) | Nature Methods
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Ghostbuster: A Phase Retrieval Diffraction Tomography Algorithm for Cryo-EM
Joel Yeo, Benedikt J. Daurer, Dari Kimanius et al. (2024) | Ultramicroscopy
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Symbolic recording of signalling and cis-regulatory element activity to DNA
Chen, W., Choi, J., Li, X. et al. (2024) | Nature
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Insights and Impact From Five Cycles of Essential Open Source Software for Science
Kate Hertweck, Carly Strasser, Dario Taraborelli (2024)
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Multidimensional Analysis of the Adult Human Heart in Health and Disease Using Hierarchical Phase-Contrast Tomography
Joseph Brunet, Andrew Cook, Claire Walsh et al. (2024) | Radiology
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Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Law, C., Wacleche, V.S., Cao, Y. et al. (2024) | Nature
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Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein
Nils Birkholz, Kotaro Kamata, Maximilian Feussner et al. (2024) | Nature
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The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
Femke M. Feringa, Sascha J. Koppes-den Hertog, Lian Wang et al. (2024) | bioRxiv
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Single-cell analysis of human diversity in circulating immune cells
Kian Hong Kock, Le Min Tan, Kyung Yeon Han et al. (2024) | bioRxiv
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Towards More Efficient Use of Electrons: Demonstrating Cryo-4D-STEM Phase Imaging Techniques on Thick and Thin Biological Specimens, from Organelles to Proteins
Yue Yu, Stephanie M Ribet, Georgios Varnavides et al. (2024) | Microscopy and Microanalysis