Research

We believe in sharing the research findings of our teams and partners openly to accelerate understanding of human health and disease. We strongly encourage researchers to deposit manuscripts as preprints before peer review to increase access to research findings and to communicate results more quickly. Since 2015, we have supported more than 8,000 publications.

75 Results
  • The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

    Femke M. Feringa, Sascha J. Koppes-den Hertog, Lian Wang et al. (2024) | bioRxiv

  • Single-cell analysis of human diversity in circulating immune cells

    Kian Hong Kock, Le Min Tan, Kyung Yeon Han et al. (2024) | bioRxiv

  • Towards More Efficient Use of Electrons: Demonstrating Cryo-4D-STEM Phase Imaging Techniques on Thick and Thin Biological Specimens, from Organelles to Proteins

    Yue Yu, Stephanie M Ribet, Georgios Varnavides et al. (2024) | Microscopy and Microanalysis

  • More Than a Phase: Uncovering the Structure of Materials with Electron Phase Retrieval Techniques

    Stephanie Ribet, Georgios Varnavides, Yue Yu et al. (2024) | Microscopy and Microanalysis

  • T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis

    Kedia, S., Ji, H., Feng, R. et al. (2024) | Nature Neuroscience

  • protoSpaceJAM: an open-source, customizable and web-accessible design platform for CRISPR/Cas insertional knock-in

    Duo Peng, Madhuri Vangipuram, Joan Wong, Manuel D Leonetti (2024) | Nucleic Acids Research

  • Mantis: high-throughput 4D imaging and analysis of the molecular and physical architecture of cells

    Ivan E. Ivanov, Eduardo Hirata-Miyasaki, Talon Chandler et al. (2024) | bioRxiv

  • Data-driven regularization lowers the size barrier of cryo-EM structure determination

    Kimanius, D., Jamali, K., Wilkinson, M.E. et al. (2024) | Nature Methods

  • Omega – harnessing the power of large language models for bioimage analysis

    Royer, L.A. (2024) | Nature Methods

  • Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury

    Malagola E, Vasciaveo A, Ochiai Y et al. (2024) | Cell

  • Genome Sequencing for Diagnosing Rare Diseases

    Monica Wojcik, Gabrielle Lemire, Eva Berger et al. (2024) | New England Journal of Medicine

  • Surforama: interactive exploration of volumetric data by leveraging 3D surfaces

    Kevin A. Yamauchi, Lorenz Lamm, Lorenzo Gaifas et al. (2024) | bioRxiv