News
May 27, 2026
Biohub releases a world model of protein biology
Biohub’s open models map the protein universe and design functional binders with therapeutic-level affinity in the lab.
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Nature: Move over, AlphaFold: open source model predicts shape of 1 billion proteins
The new open-source atlas, generated by an AI tool called ESMFold2, vastly increases the known protein universe.
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Biology’s blind spot
Inflammation drives nearly every major disease, yet we’ve never been able to directly watch it progress in living tissue. These researchers are building the technologies to change that.
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The immune cell engineers
Fifteen research teams are building the molecular toolkit to reprogram the body’s own defenders across diverse disease areas.
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Biohub Launches the Virtual Biology Initiative to Galvanize a Global Effort to Create the Open Data Foundation for AI-Accelerated Biology
A $500 million commitment — and a call for the global scientific community to join — aims to unlock predictive models of the human cell to accelerate the cure and prevention of all disease.
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Axios Exclusive: Zuckerberg-backed Biohub bets $500M on AI biology
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Time: If AI Can Model Cells, Science Can Deliver Cures
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Chronicle of Philanthropy: How Small Grants Can Bridge a Gap — and Lead to Big Changes
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Inside Philanthropy: CZI Is Poised to Become the World’s Largest Private Biomedical Funder. What Might That Look Like?
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New Biohub Investigators Will Engineer Immune-Cell ‘Scouts’ to Detect Disease at Earliest Stages
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Inside Philanthropy: New Gene Therapy Trial Moves Forward Thanks to Chan Zuckerberg Initiative
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The Scientist: Three amino acids improve lipid nanoparticle therapy delivery to cells
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Simple ‘Cocktail’ of Amino Acids Dramatically Boosts Power of Anti-Inflammatory mRNA Therapies and CRISPR Gene Editing
Adding three common amino acids to lipid nanoparticle injections increased mRNA delivery up to 20-fold, pushed gene editing efficiency to nearly 90%, and suppressed inflammation in a model of acute liver disease.